Targin (oxycodone/naloxone) 5mg/2.5mg from Mundipharma

€301.00

Commercial Name: Targin

Production form: pills

Utilization: pain relief

Available Dosages: 5mg/2.5mg

Sku:

N/A

Description

What Targin is and what it is used for
Targin is a prolonged-release tablet, which means that its active substances are released over an extended
period. Their action lasts for 12 hours.
These tablets are only for use in adults.
Pain relief
You have been prescribed Targin for the treatment of severe pain, which can be adequately managed only
with opioid analgesics. Naloxone hydrochloride is added to counteract constipation.
How these tablets work in pain relief
These tablets contain oxycodone hydrochloride and naloxone hydrochloride as active substances. Oxycodone
hydrochloride is responsible for the pain-killing effect of Targin, and is a potent analgesic (“painkiller”) of
the opioid group. The second active substance of Targin, naloxone hydrochloride, is intended to counteract
constipation. Bowel dysfunction (e.g. constipation) is a typical side effect of treatment with opioid
painkillers.
Restless legs syndrome
You have been prescribed Targin for the second line symptomatic treatment of severe to very severe restless
legs syndrome in people who can’t be treated with dopamine medicines. People with restless legs syndrome
have unpleasant sensations in their limbs. This can start as soon as they sit or lie down and is only relieved
by an irresistible urge to move the legs, sometimes the arms and other parts of the body. It makes sitting still
and sleeping very difficult. Naloxone hydrochloride is added to counteract constipation.
How these tablets work in restless legs syndrome
These tablets help to relieve the unpleasant sensations and so reduces the urge to move the limbs.
The second active substance of Targin, naloxone hydrochloride, is intended to cou
The second active substance of Targin, naloxone hydrochloride, is intended to counteract constipation.
Bowel dysfunction (e.g. constipation) is a typical side effect of treatment with opioids.
2. What you need to know before you take Targin
Do not take Targin
• if you are allergic to oxycodone hydrochloride, naloxone hydrorochloride or any of the other
ingredients of this medicine (listed in section 6),
• if your breathing is not able to supply enough oxygen to the blood, and get rid of carbon dioxide
produced in the body (respiratory depression),
• if you suffer from a severe lung disease associated with narrowing of the airways (chronic obstructive
pulmonary disease or COPD),
• if you suffer from a condition known as cor pulmonale. In this condition the right side of the heart
becomes enlarged, due to increased pressure inside blood vessels in the lung etc (e.g. as a result of
COPD – see above),
• if you suffer from severe bronchial asthma,
• if you have paralytic ileus (a type of bowel obstruction) not caused by opioids,
• if you have moderate to severe liver dysfunction.